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Cat No. | Product Name | Synonyms | Targets |
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T24986 | 6bK | 6 bK,6-bK,IDE inhibitor 6bK,IDE-IN-6bK,IDE-inhibitor-6bK | |
6bK is an inhibitor of insulin degrading enzyme (IDE). | |||
T25142 | BDM44768 | BDM 44768,BDM-44768 | |
BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance. | |||
T35802 | ML-345 | ||
Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling. [1] In addition to regulating insulin a... | |||
T83802 | TNP-ATP sodium | ||
TNP-ATP, a derivative of ATP, acts as an antagonist to the purinergic P2Y1, P2X3, and P2X2/3 receptors, demonstrating selectivity by showing lower inhibitory concentrations (IC50 = 6, 0.9, 7 nM, respectively) compared to... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00851 | IDE Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a r... | |||
TMPH-02342 | Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc) | Hypoderma lineatum | E. coli |
This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-|-Try-16 and 22-Arg-|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P... |